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TRPV
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TRPV (vanilloid) channels are composed of two subfamilies which are non-selective cation channels (TRPV1-4) and the more calcium selective channels (TRPV5/6). TRPV channels have been implicated in pain, cancer, immunity and neurodegenerative disorders.
PD 0325901 (HB2240)
Description:Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.
Purity:>98%
SB 431542 (HB3555)
Description:Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.
Purity:>98%