Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 61-70 of 312

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  1. Cyclopamine (HB2965)

    Description:

    Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $196
    Qty:
    Pack:
    5mg
    Price:
    $746
    Qty:
  2. Description:

    Potent SERCA1a inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $95
    Qty:
    Pack:
    50mg
    Price:
    $451
    Qty:
  3. Cyclosporin A (HB0220)

    Description:

    Potent calcineurin inhibitor. Inhibits MPTP opening.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $96
    Qty:
  4. Pack:
    10mg
    Price:
    $213
    Qty:
    Pack:
    50mg
    Price:
    $827
    Qty:
  5. Pack:
    100mg
    Price:
    $147
    Qty:
    Pack:
    500mg
    Price:
    $591
    Qty:
  6. Pack:
    5mg
    Price:
    $78
    Qty:
    Pack:
    25mg
    Price:
    $311
    Qty:
    Pack:
    10mg
    Price:
    $74
    Qty:
  7. Description:

    Selective serotonin reuptake inhibitor (SSRI)

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $116
    Qty:
    Pack:
    50mg
    Price:
    $414
    Qty:
  8. DAPT (HB3345)

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    Description:

    γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $168
    Qty:
    Pack:
    25mg
    Price:
    $418
    Qty:
    Pack:
    50mg
    Price:
    $703
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $109
    Qty:
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