Histone deacetylase (HDAC)
Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.
Anti-α-Synuclein antibody ValidAbTM (HB6378)
Description:Antibody to Alpha-Synuclein - synaptic protein involved in neurodegeneration. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat -
Anti-Calbindin antibody ValidAbâ„¢ (HB6396)
Description:Antibody to Calbindin - calcium binding protein used as a marker for an inhibitory interneuron subtype. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Rat -
Anti-GFAP antibody ValidAbâ„¢ (HB7592)
Description:Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: GoatClonality: PolyclonalReactivity Tested: Mouse, Rat -
Anti-GluN1 antibody ValidAbTM (HB7535)
Description:Antibody to the GluN1 subunit of the NMDA receptor. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat -
Anti-NeuN antibody ValidAbâ„¢ (HB9493)
Description:Antibody to NeuN - marker for mature neurones expressed in the nucleus. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: GoatClonality: PolyclonalReactivity Tested: Mouse, Rat - Description:
Antibody to βIII Tubulin - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat - Description:
Immunofluorescent signal amplification kit using biotin tyramide and Streptavidin AF488.
- Description:
Immunofluorescent signal amplification kit using biotin tyramide and Streptavidin Janelia Fluor® 525.
- Description:
Immunofluorescent signal amplification kit using biotin tyramide and Streptavidin Janelia Fluor® 549.
