Target

K_2P2.1 (TREK-1) modulator. Selectively and irreversibly activates TREK-1^CG* but not wild-type K_2P2.1 (TREK-1)

Selective mGlu₅ positive allosteric modulator

β-lactam antibiotic. Increases EAAT2 activity.

Anti-oxidant, anti-inflammatory compound with many actions. Topoisomerase II inhibitor.

Potent and specific PKC inhibitor

Potassium channel blocker. Component in cesium gluconate-based internal solutions used for patch clamp electrophysiology.

Selective M₁ receptor agonist

Selective, non-competitive AMPA receptor antagonist

Selective GABA_B receptor antagonist

Potent, selective mitochondria Na⁺ / Ca²⁺ exchange inhibitor