Target

Water soluble, non-selective group I and II mGluR antagonist

Potent and selective 5-HT_2A receptor antagonist

Non-competitive NMDA receptor antagonist

Non-selective 5-HT₂ receptor antagonist. Shows activity at other receptors.

Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.

NMDA receptor antagonist. Less active enantiomer of (+)-MK 801.

Potent, selective, non-competitive NMDA receptor antagonist

Novel caged, fast-equilibrating glutamate receptor antagonist. Suitable for use as a synaptic probe.

5-HT₄ receptor agonist. Also 5-HT₃ antagonist.

Potent, selective mGluR₅ antagonist / mGluR₄ positive allosteric modulator