Target

Water soluble, non-selective group I and II mGluR antagonist

Potent and selective 5-HT_2A receptor antagonist

Potent and selective 5-HT_2A receptor antagonist. Water soluble.

Non-competitive NMDA receptor antagonist

Potent, selective α7 nicotinic receptor antagonist

Non-selective 5-HT₂ receptor antagonist. Shows activity at other receptors.

Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.

Potent, selective, non-competitive NMDA receptor antagonist

Less active enantiomer of (+)-MK 801. NMDA receptor antagonist.

Novel caged, fast-equilibrating glutamate receptor antagonist. Suitable for use as a synaptic probe.