TLR (Toll-like receptors)
Toll-like receptors (TLRs) are found on various immune cells and are essential in the innate immune response. TLRS signal through the recruitment of specific adaptor molecules which leads to NF-kB and IRF activation. Researchers can save up to 50% on TLR ligands from Hello Bio - they are around half the price of other suppliers.
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Brefeldin A (BFA) (HB2949)
Description:Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.
Purity:>98%
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- Description:
Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.
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MCC950 sodium salt (HB4636)
Description:Potent, selective NLRP3 inflammasome inhibitor
Purity:>98%
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Pam3CSK4 (HB3428)
Description:TLR1/TLR2 agonist and potent NF-κB activator. Induces cytokine production.
