JAK/STAT

JAK/STAT signaling plays a critical role in the immune response. It is plays a major role in transferring signals from cell-membrane receptors to the nuclear. The JAK/STAT signaling pathway is essential for a wide range of cytokines and growth factors which lead to critical immunological cellular events.
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  1. Pack:
    1g
    Price:
    $34
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    Pack:
    5g
    Price:
    $67
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  2. CCG 1423 (HB3389)

    Description:

    Rho/SRF pathway inhibitor. Induces intermediate mesoderm differentiation from ESCs.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $117
    Qty:
    Pack:
    50mg
    Price:
    $433
    Qty:
  3. CHIR 99021 (HB1261)

    Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $50
    Qty:
    Pack:
    2mg
    Price:
    Qty:
    Pack:
    5×2mg
    Price:
    $188
    Qty:
    Pack:
    10mg
    Price:
    $182
    Qty:
    Pack:
    5mg
    Price:
    $117
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    Pack:
    25mg
    Price:
    $445
    Qty:
    Pack:
    50mg
    Price:
    $758
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $126
    Qty:
  4. Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons. Water soluble.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $229
    Qty:
    Pack:
    50mg
    Price:
    $916
    Qty:
  5. Description:

    STAT3 inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $83
    Qty:
    Pack:
    25mg
    Price:
    $205
    Qty:
    Pack:
    50mg
    Price:
    $376
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    Pack:
    100mg
    Price:
    $677
    Qty:
  6. Cyclopamine (HB2965)

    Description:

    Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $205
    Qty:
    Pack:
    5mg
    Price:
    $779
    Qty:
  7. Cyclosporin A (HB0220)

    Description:

    Potent calcineurin inhibitor. Inhibits MPTP opening.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $100
    Qty:
  8. DAPT (HB3345)

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    Description:

    γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $103
    Free trial
    Qty:
    Pack:
    10mg
    Price:
    $175
    Qty:
    Pack:
    25mg
    Price:
    $436
    Qty:
    Pack:
    50mg
    Price:
    $733
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $114
    Qty:
  9. Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $153
    Qty:
    Pack:
    10mg
    Price:
    $193
    Qty:
    Pack:
    50mg
    Price:
    $806
    Qty:
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