JAK/STAT

JAK/STAT signaling plays a critical role in the immune response. It is plays a major role in transferring signals from cell-membrane receptors to the nuclear. The JAK/STAT signaling pathway is essential for a wide range of cytokines and growth factors which lead to critical immunological cellular events.
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  1. A83-01 (HB3218)

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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $92
    Qty:
    Pack:
    25mg
    Price:
    $310
    Qty:
  2. Pack:
    5mg
    Price:
    $320
    Qty:
    Pack:
    25mg
    Price:
    $1,049
    Qty:
  3. Arctigenin (HB0119)

    Description:

    Potent MAP kinase kinase (MKK/MEK) inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $154
    Qty:
    Pack:
    50mg
    Price:
    $298
    Qty:
    Pack:
    100mg
    Price:
    $462
    Qty:
  4. 5-Azacytidine (HB1374)

    Description:

    DNA methyltransferase inhibitor. Improves stem cell reprogramming efficiency and induces differentiation of MSCs into cardiomyocytes.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $70
    Qty:
    Pack:
    250mg
    Price:
    $97
    Qty:
  5. BIO (HB1259)

    Description:

    Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $292
    Qty:
    Pack:
    25mg
    Price:
    $653
    Qty:
  6. BIX 01294 (HB1413)

    Description:

    Potent, selective GLP / G9a HMTase inhibitor. Potentiates iPSC induction.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $215
    Qty:
    Pack:
    50mg
    Price:
    $751
    Qty:
  7. Pack:
    10mg
    Price:
    $102
    Qty:
    Pack:
    50mg
    Price:
    $378
    Qty:
  8. Description:

    Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $110
    Qty:
    Pack:
    25mg
    Price:
    $481
    Qty:
  9. Pack:
    10μg
    Price:
    $182
    Qty:
  10. Description:

    Serine protease inhibitor. Inhibits TMPRSS2 and partially blocks SARS-Cov2 entry in vitro.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    Qty:
    Pack:
    50mg
    Price:
    $154
    Qty:
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