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Inflammasome

Inflammasomes are an important part of the innate immune system which are activated upon cellular infection or stress to trigger maturation of proinflammatory cytokines. They regulate the activation of caspase-1 and induce an inflammatory response.
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  1. Anti-Histone H3 antibody ValidAbâ„¢ (HB6980)

    Description:

    Antibody to Histone H3 - Histone protein used as a loading control for western blotting. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. Histone H3 expression in various tissue lysates and preparations.
    Pack:
    25μL
    Price:
    $196
    Qty:
    Pack:
    100μL
    Price:
    $438
    Qty:
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  2. Anti-HSP60 antibody ValidAbâ„¢ (HB7863)

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    Description:

    Antibody to HSP60 - loading control and mitochondrial marker for immunohistochemistry and immunocytochemistry. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat, Human
    Figure 1. HSP60 staining with HB7863 reveals the dense mitochondria in cultured rat neurones.
    Pack:
    25μg
    Price:
    $160
    Qty:
    Pack:
    100μg
    Price:
    $363
    Qty:
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  3. Anti-Ki-67 antibody ValidAbTM (HB7052)

    Description:

    Antibody to Ki-67 - a widely used marker of proliferating cells. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Human
    Figure 1. Ki-67 expression in proliferating HEK293T cells
    Pack:
    25μg
    Price:
    $139
    Qty:
    Pack:
    100μg
    Price:
    $310
    Qty:
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  4. Anti-MAP2 antibody ValidAbTM (HB9587)

    Description:

    Antibody to MAP2 - cytoskeletal protein used as a neuronal marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. MAP2 expression in cultured rat neurones visualised using HB9587.
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $320
    Qty:
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  5. Anti-mCherry Antibody ValidAbâ„¢ (HB6512)

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    Description:

    Antibody to mCherry - red coloured fluorescent protein widely used as a tag in molecular biology

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Species Independent
    Figure 1. pmCherry-C3 transfected HEK293 cells showing co-localised staining of mCherry and HB6512.
    Pack:
    25μg
    Price:
    $174
    Qty:
    Pack:
    100μg
    Price:
    $388
    Qty:
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  6. Anti-Myelin Basic Protein (MBP) Antibody ValidAbâ„¢ (HB8014)

    Description:

    Antibody to myelin basic protein (MBP) - marker for oligodendrocytes and Schwann cells. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Rat, Mouse (no staining)
    MBP staining in the rat cerebellum
    Pack:
    25μg
    Price:
    $144
    Qty:
    Pack:
    100μg
    Price:
    $320
    Qty:
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  7. Anti-NeuN antibody ValidAbâ„¢ (HB6429)

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    Description:

    Antibody to NeuN - marker for mature neurones expressed in the nucleus. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Anti-NeuN antibody ValidAb™
    Pack:
    25μg
    Price:
    $163
    Qty:
    Pack:
    100μg
    Price:
    $366
    Qty:
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  8. Anti-NeuN antibody ValidAbâ„¢ (HB6498)

    Description:

    Antibody to NeuN - marker for mature neurones expressed in the nucleus. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Figure 2. NeuN expressing neurons in the rat hippocampus visualised using HB6498
    Pack:
    25μg
    Price:
    $153
    Qty:
    Pack:
    100μg
    Price:
    $372
    Qty:
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  9. Anti-Neurofilament L (NF-L) antibody ValidAbâ„¢ (HB6433)

    Description:

    Antibody to Neurofilament L - neurofilament component expressed in neurones. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Figure 1. Neurofilament L expression in cultured rat neurones visualised using HB6433.
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
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  10. Recombinant Anti-Neurofilament L (NF-L) antibody ValidAbTM (HB7266)

    Description:

    Recombinant antibody to Neurofilament L - neurofilament component expressed in neurones. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Neurofilament L expression in a cultured rat neuron visualised using HB7266
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
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Biological action
  1. Buffer
  2. Dyes & stains
Applications
  1. Antineoplastic Agent
  2. Cell Culture
  3. ELISA
  4. FACS and flow cytometry
  5. fluorescence imaging
  6. ICC
  7. IF
  8. IHC
  9. IHC-P
  10. live cell imaging
  11. Plant Culture
  12. Selection Agent
  13. WB
  14. IHC(IF)
  15. Histoblot
  16. SDS-PAGE
Host
  1. Mouse
  2. Rabbit
  3. Goat
  4. Chicken
Clonality
  1. Monoclonal
  2. Polyclonal
Conjugate
  1. Horseradish peroxidase (HRP)
  2. Janelia Fluor® 646
  3. Biotin
Target
  1. GluN1
  2. GFAP
  3. GAPDH
  4. NeuN
  5. mCherry
  6. Neurofilament L
  7. Beta III tubulin
  8. HSP60
  9. Neurofilament M
  10. GFP
  11. MAP2
  12. Tyrosine hydroxylase
  13. β-tubulin
  14. Myelin basic protein
  15. GAT1
  16. Vimentin
  17. Mouse IgG H&L
  18. Rabbit IgG H&L
  19. GST tag
  20. VGAT
  21. Calretinin
  22. Histone H3
  23. Ki-67
  24. Chicken IgY H&L
  25. GluA1-4
  26. Biotin