Cytokines, chemokines & NF-κB/I-κB
Cytokines and chemokines play an important role in inflammation and act as key modulators of inflammation by acting through a variety of pathways and interactions. Proinflammatory cytokines activate the IKK complex and closely interact with NF-κB and JAK/STAT signaling. Researchers can make big savings on Hello Bio's cytokines and chemokines modulators, our prices are around 25-50% less than other suppliers.
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Brefeldin A (BFA) (HB2949)
Description:Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.
Purity:>98%
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Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.
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MCC950 sodium salt (HB4636)
Description:Potent, selective NLRP3 inflammasome inhibitor
Purity:>98%
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Pam3CSK4 (HB3428)
Description:TLR1/TLR2 agonist and potent NF-κB activator. Induces cytokine production.
