Cytokine Storm / Immune response signaling

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Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.

View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling

Items 1-10 of 13

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  1. A83-01 (HB3218)

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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $88
    Qty:
    Pack:
    25mg
    Price:
    $297
    Qty:
  2. AG 490 (HB1424)

    Description:

    Selective EGF receptor tyrosine kinase inhibitor

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $473
    Qty:
  3. Pack:
    10mg
    Price:
    $213
    Qty:
    Pack:
    50mg
    Price:
    $827
    Qty:
  4. Pack:
    5mg
    Price:
    $78
    Qty:
    Pack:
    25mg
    Price:
    $311
    Qty:
    Pack:
    10mg
    Price:
    $74
    Qty:
  5. Pack:
    10mg
    Price:
    $208
    Qty:
  6. ITD 1 (HB3446)

    Description:

    Selective TGF-β signaling inhibitor. Induces cardiomyocyte differentiation in ESCs.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $213
    Qty:
    Pack:
    50mg
    Price:
    $824
    Qty:
  7. Pack:
    10mg
    Price:
    $266
    Qty:
    Pack:
    50mg
    Price:
    $1,107
    Qty:
  8. PD 173074 (HB3584)

    Description:

    FGFR1/ FGFR3 inhibitor. Inhibits oligodendrocyte progenitor proliferation and differentiation.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $215
    Qty:
    Pack:
    50mg
    Price:
    $835
    Qty:
  9. PP 3 (HB1336)

    Description:

    PP 2 negative control

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $208
    Qty:
    Pack:
    50mg
    Price:
    $844
    Qty:
  10. RepSox (HB3301)

    Description:

    Potent, selective TGF-βRI inhibitor. Enhances cellular reprogramming efficiency.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $134
    Qty:
    Pack:
    25mg
    Price:
    $279
    Qty:
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