Cytokine Storm / Immune response signaling

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Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.

View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling

Items 1-10 of 12

Set Descending Direction
  1. GSK'872 (HB5933)

    Description:

    Potent, selective RIP3 inhibitor. Necroptosis inhibitor.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $135
    Qty:
    Pack:
    50mg
    Price:
    $567
    Qty:
    Pack:
    10mM solution (in 1mL DMSO)
    Price:
    $88
    Qty:
  2. MG132 (HB4135)

    Description:

    Potent, cell-permeable proteasome inhibitor. Calpain inhibitor. Apoptosis inducer.

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $103
    Qty:
    Pack:
    25mg
    Price:
    $300
    Qty:
  3. Description:

    Highly selective, pan-Akt inhibitor. Autophagy and apoptosis inducer. Orally bioavailable.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $58
    Qty:
    Pack:
    10mg
    Price:
    $77
    Qty:
    Pack:
    50mg
    Price:
    $325
    Qty:
    Pack:
    10mM solution (in 1mL DMSO)
    Price:
    $125
    Qty:
  4. Pifithrin-μ (HB3025)

    Description:

    p53 inhibitor. Supresses eSC self renewal and may increase stem cell reprogramming efficiency.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $95
    Qty:
    Pack:
    25mg
    Price:
    $382
    Qty:
  5. Pack:
    1mg
    Price:
    $408
    Qty:
  6. Pack:
    1mg
    Price:
    $51
    Qty:
    Pack:
    5mg
    Price:
    $124
    Qty:
    Pack:
    10mg
    Price:
    $143
    Qty:
    Pack:
    50mg
    Price:
    $600
    Qty:
  7. Pack:
    5mg
    Price:
    $90
    Qty:
    Pack:
    25mg
    Price:
    $350
    Qty:
  8. Z-DEVD-FMK (HB1282)

    Description:

    Irreversible, selective caspase 3 inhibitor

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $299
    Qty:
    Pack:
    5mg
    Price:
    $1,211
    Qty:
  9. Z-DQMD-FMK (HB1283)

    Description:

    Cell permeable caspase 3 specific inhibitor

    Pack:
    1mg
    Price:
    $293
    Qty:
    Pack:
    5mg
    Price:
    $1,189
    Qty:
  10. Pack:
    1mg
    Price:
    $196
    Qty:
    Pack:
    5mg
    Price:
    $678
    Qty:
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