PSEMS

Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.

Potent, specific cAMP-dependent protein kinases activator. Cell-permeable.

K_2P2.1 (TREK-1) modulator. Selectively and irreversibly activates TREK-1^CG* but not wild-type K_2P2.1 (TREK-1)

Prototypical DREADD activator. Clozapine metabolite.

Dihydrochloride salt of CNO - the prototypical DREADD activator

Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).

Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).

mTOR activator and autophagy inhibitor. Cell-permeable.

Covalent K_2P2.1 (TREK-1) modulator

Caged glutamate that rapidly and efficiently releases glutamate when photolysed