Caged compounds
Caged compounds are biomolecules whose activity can be modulated and controlled by light. The biomolecule is temporarily inactivated by being bound to a photolabile chemical group (a 'cage'). The application of light (visible or infra-red) removes this cage and enables the biologically active molecule to be released (photoreleased). These light-sensitive probes offer an enhanced way of controlling the timing and location of administration of these compounds and subsequent activation or inhibition of their biological target. Researchers can save up to 50% on caged compounds from Hello Bio - they are up to half the price of other suppliers.
- Description:
Neurotoxin, widely used to produce the 6-OHDA Parkinson’s disease model
Purity:>98%
A83-01 (HB3218)
Description:Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Purity:>98%
AM 404 (HB1174)
Description:Selective, competitive carrier-mediated anandamide transport inhibitor
Purity:>98%
Amitriptyline hydrochloride (HB1794)
Description:Serotonin/norepinephrine reuptake inhibitor (SNRI)
Purity:>98%
(±)-Anatoxin A fumarate (HB2023)
Description:Potent nicotinic agonist. Apoptosis inducer.
Purity:>99%
Aniracetam (HB0116)
Description:Nootrophic AMPA receptor positive allosteric modulator
Purity:>98%
DL-AP4 Sodium salt (HB0250)
Description:Water soluble form of DL-AP4, non-selective glutamate antagonist
Purity:>99%
D-AP5 (HB0225)
Description:Selective, competitive NMDA receptor antagonist. Inhibits NMDAR-synaptic plasticity.
Purity:>99%