Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
EHNA hydrochloride (HB3540)
Description:Potent adenosine deaminase and PDE2 inhibitor. Supresses spontaneous hESC differentiation. Also maintains pluripotency of hESCs in the absence of exogenous cytokines.
Purity:>98%
Eliprodil (HB0274)
Description:Non-competitive, GluN2B subunit selective NMDA receptor antagonist
Purity:>98%
Empagliflozin (HB4638)
Description:Potent, selective sodium glucose co-transporter 2 (SGLT-2) inhibitor
Purity:>98%
epi-Aszonalenin A (HB3889)
Description:Derivative of aszonalenin, a substance P inhibitor.
Purity:>95%
Epoxomicin (HB3890)
Description:Potent, selective and irreversible 20S proteasome inhibitor
Purity:>97%