Glutamate uptake & transport
Glutamate transport is mediated by a family of transmembrane proteins known as glutamate transporters, or excitatory amino acid transporters (EAATs). EAATs are sodium- and potassium-dependent members of the Solute Carrier Family 1 (SLC1). The five EAAT subtypes are EAAT1 (Excitatory amino acid transporter 1 / SLC1A3) , EAAT2 (Excitatory amino acid transporter 2 / SLC1A2), EAAT3 (Excitatory amino acid transporter 3 / SLC1A1), EAAT4 (Excitatory amino acid transporter 4 / SLC1A6) and EAAT5 (Excitatory amino acid transporter 5 / SLC1A7). Researchers can save up to 50% on EAAT inhibitors, activators and modulators from Hello Bio - they are up to half the price of other suppliers.
- Description:
Neurotoxin, widely used to produce the 6-OHDA Parkinson’s disease model
Purity:>98%
A83-01 (HB3218)
Description:Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Purity:>98%
AM 404 (HB1174)
Description:Selective, competitive carrier-mediated anandamide transport inhibitor
Purity:>98%
Amitriptyline hydrochloride (HB1794)
Description:Serotonin/norepinephrine reuptake inhibitor (SNRI)
Purity:>98%
(±)-Anatoxin A fumarate (HB2023)
Description:Potent nicotinic agonist. Apoptosis inducer.
Purity:>99%
Aniracetam (HB0116)
Description:Nootrophic AMPA receptor positive allosteric modulator
Purity:>98%
DL-AP4 Sodium salt (HB0250)
Description:Water soluble form of DL-AP4, non-selective glutamate antagonist
Purity:>99%
D-AP5 (HB0225)
Description:Selective, competitive NMDA receptor antagonist. Inhibits NMDAR-synaptic plasticity.
Purity:>99%