Glutamate uptake & transport
Glutamate transport is mediated by a family of transmembrane proteins known as glutamate transporters, or excitatory amino acid transporters (EAATs). EAATs are sodium- and potassium-dependent members of the Solute Carrier Family 1 (SLC1). The five EAAT subtypes are EAAT1 (Excitatory amino acid transporter 1 / SLC1A3) , EAAT2 (Excitatory amino acid transporter 2 / SLC1A2), EAAT3 (Excitatory amino acid transporter 3 / SLC1A1), EAAT4 (Excitatory amino acid transporter 4 / SLC1A6) and EAAT5 (Excitatory amino acid transporter 5 / SLC1A7). Researchers can save up to 50% on EAAT inhibitors, activators and modulators from Hello Bio - they are up to half the price of other suppliers.
A83-01 (HB3218)
Description:Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Purity:>98%
AM 404 (HB1174)
Description:Selective, competitive carrier-mediated anandamide transport inhibitor
Purity:>98%
Amitriptyline hydrochloride (HB1794)
Description:Serotonin/norepinephrine reuptake inhibitor (SNRI)
Purity:>98%
CGP 37157 (HB1132)
Description:Potent, selective mitochondria Na+ / Ca2+ exchange inhibitor
Purity:>99%
p-Chlorophenylalanine (HB1647)
Description:Irreversible tryptophan hydroxylase inhibitor. Depletes 5-HT.
Purity:>99%
Cyclopamine (HB2965)
Description:Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.
Purity:>98%