Transporters
Transporters are integral transmembrane proteins involved in the movement of ions, small molecules, peptides, lipids or macromolecules, such as another protein, across a biological membrane. The energy required for active transport processes is obtained by hyrdolyzing ATP or by utilising ion gradients. The three major classes of ATP-driven transporters are: P-type ATPases (eg. Ca2+-ATPases and Na+,K+-ATPases); F-type or V-type ATPases and ATP-binding cassette transporters. The solute carrier family of transporters include the biogenic amine transporters (NET, DAT and SERT) the Na+/H+ exchanger, glutamate transporters (EAAT) and GABA transporters (GAT). Researchers can save up to 50% on transporter blockers and inhibitors from Hello Bio – they are up to half the price of other suppliers and have been reviewed and cited by researchers worldwide.
View transporter products: Cannabinoid | Dopamine | GABA | Glutamate | Glycine | Monoamine | Multidrug Transporter | Na+ / Ca2+ exchangers | Na+ / H+ exchangers | Norepinephrine | Serotonin (5-HT)
RepSox (HB3301)
Description:Potent, selective TGF-βRI inhibitor. Enhances cellular reprogramming efficiency.
Purity:>99%
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SB 431542 (HB3555)
Description:Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.
Purity:>98%
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Sertraline hydrochloride (HB1717)
Description:Potent, selective 5-HT re-uptake inhibitor (SSRI)
Purity:>98%
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SKF 89976A hydrochloride (HB0976)
Description:Potent, selective, competitive GAT-1 GABA uptake inhibitor
Purity:>99%
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SU 5402 (HB3133)
Description:Potent FGFR and VEGFR inhibitor. Attenuates integrin β4-induced neural stem cell differentiation.
Purity:>95%
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Tetrabenazine (HB1711)
Description:Potent inhibitor of vesicular monoamine transport; depletes 5-HT stores
Purity:>98%
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UCPH 101 (HB0630)
Description:UCPH-101 is a potent, selective, non-competitive EAAT1 inhibitor
Purity:>98%
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