Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.
GYKI 52466 hydrochloride (HB0311)
Description:Selective, non-competitive AMPA receptor antagonist
Purity:>98%
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GYKI 53655 hydrochloride (HB0312)
Description:Non-competitive AMPA receptor antagonist. Also blocks kainate GluK3 homomeric receptors.
Purity:>98%
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Haloperidol hydrochloride (HB1842)
Description:Dopamine receptor antagonist with partial D2-like selectivity
Purity:>99%
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Hoechst 33342 (HB0787)
Description:Blue fluorescent DNA stain. Cell permeable. Nuclear stain.
Purity:>98%
- Description:
Blue fluorescent DNA stain. Nuclear stain. 10mg/ml staining solution in water. Solid also available in 50mg and 100mg.
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- Description:
Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).
Purity:>98%
- Description:
Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).
Purity:>98%
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Hyperforin dicyclohexylammonium (HB3933)
Description:Selective TRPC6 channel activator and neurotransmitter re-uptake inhibitor
Purity:>97%
