DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
- Description:
Identifies early apoptotic, necrotic and viable cells
- Description:
Detects apoptosis by staining phosphatidylserine molecules translocated to the outside of the cell membrane.
Cycloheximide (HB2904)
Description:Eukaryotic protein synthesis inhibitor. Apoptosis inducer.
Purity:>95%
G418 disulfate salt (HB3906)
Description:Antibiotic. Widely used in cell culture. Protein synthesis inhibitor.
Puromycin dihydrochloride (HB4041)
Description:Protein synthesis inhibitor. Cell culture selection antibiotic.
Purity:>98%