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G418 disulfate salt

(HB3906)
Publications (1)
Technical documents: SDS CoA Datasheet
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Product overview

Name G418 disulfate salt
Description Antibiotic. Widely used in cell culture. Protein synthesis inhibitor.
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews (1) Publications (1) References (3) Frequently bought together
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Biological Data

Biological description

Antibiotic. Inhibits protein synthesis to show cytotoxic activity.

Widely used in cell culture as a selection antibiotic for the selection of eukaryotic expression vectors, in combination with either aminoglycoside phosphotransferase 3' or APH II.

Also shows antiviral activity and induces apoptosis.

Solubility & Handling

Solubility overview Soluble in water (100 mM)
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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x
More Info

Dilution

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x
More Info

Chemical Data

Chemical name O-2-Amino-2,7-dideoxy-D-glycero-α-D-glucoheptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-D-streptamine sulfate
Molecular Weight 692.71
Chemical structure G418 disulfate salt [108321-42-2] Chemical Structure
Molecular Formula C20H40N4O10.2H2SO4
CAS Number 108321-42-2
PubChem identifier 16218858
SMILES CC([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@H]3[C@H]([C@@H]([C@](CO3)(C)O)NC)O)N)N)N)O)O)O.OS(=O)(=O)O.OS(=O)(=O)O
InChi InChI=1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1
InChiKey UHEPSJJJMTWUCP-DHDYTCSHSA-N
MDL number MFCD00058314
Appearance White solid

References for G418 disulfate salt

References are publications that support the biological activity of the product

  • A novel kanamycin/G418 resistance marker for direct selection of transformants in Escherichia coli and different yeast species.

    Agaphonov et al (2010) Yeast 27(4) : 189-95
    Read more (PubMedID: 20014045)

  • The effects of G418 on the growth and metabolism of recombinant mammalian cell lines.

    Yallop and Svendsen (2001) Cytotechnology 35(2) : 101-14
    Read more (PubMedID: 19003287)

  • Use of plasmid-mediated resistance to the antibiotic G418 for the rapid screening of a yeast mutant library.

    Chenevert et al (1984) J Exp Pathol 1(4) : 307-13
    Read more (PubMedID: 6400641)

3 Item(s)

Publications
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These publications cite the use of G418 disulfate salt purchased from Hello Bio:

  • Development of High-Throughput Fluorescent-Based Screens to Accelerate Discovery of P2X Inhibitors from Animal Venoms

    Bibic L et al (2019) J Nat Prod 82(9) : 2559-2567
    PubMedID: 31532206

1 Item

Related Products
Grouped product items
Order: HB3906
Pack PriceQty
250mg
$43
1g
$89
Antibiotic. Widely used in cell culture. Protein synthesis inhibitor.
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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