G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Anti-Calretinin antibody ValidAbTM (HB6494)
Description:Antibody to Calretinin - calcium binding protein used as a marker for an inhibitory interneuron subtype. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, RatAnti-GAT1 Antibody ValidAb™ (HB7632)
Description:Antibody to GAT1 - GABA reuptake transporter and marker for GABAergic interneurones. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, RatAnti-GFAP antibody ValidAbTM (HB8001)
Description:Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, RatAnti-GFP antibody ValidAbTM (HB8912)
Description:Antibody to GFP - green coloured fluorescent protein widely used as a tag in molecular biology. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Species IndependentAnti-Histone H3 antibody ValidAb™ (HB6980)
Description:Antibody to Histone H3 - Histone protein used as a loading control for western blotting. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, RatAnti-IBA1 antibody ValidAbTM (HB7847)
Description:Antibody to IBA1 - calcium binding protein widely used as a marker for microglial cells. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, RatAnti-mCherry Antibody ValidAb™ (HB6512)
Description:Antibody to mCherry - red coloured fluorescent protein widely used as a tag in molecular biology
Host: RabbitClonality: PolyclonalReactivity Tested: Species IndependentAnti-NeuN antibody ValidAb™ (HB6498)
Description:Antibody to NeuN - marker for mature neurones expressed in the nucleus. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, Rat- Description:
Recombinant antibody to Neurofilament L - neurofilament component expressed in neurones. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: MonoclonalReactivity Tested: Mouse, Rat - Description:
Antibody to tyrosine hydroxylase (TH) - the rate limiting enzyme in catecholamine synthesis and used as a marker for catecholaminergic (dopaminergic and noradrenergic) neurones in the CNS. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, Rat