Receptors & Transporters

Potent glucocorticoid and progesterone receptor antagonist. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.

5-HT₄ receptor agonist. Also 5-HT₃ antagonist.

Potent, selective mGluR₅ antagonist / mGluR₄ positive allosteric modulator

Selective ERα estrogen receptor antagonist

Selective P2Y₁ antagonist. Inhibits platelet aggregation.

Potent, selective P2Y₆ receptor antagonist

Potent, highly selective, non-competitive mGluR₅ antagonist

5-HT_2A and D₂ antagonist. Potent DREADD agonist. Atypical antipsychotic.

PAR₄ antagonist. Inhibits platelet aggregation.

5-HT_2A and D₂ antagonist. Antipsychotic.