Receptors & Transporters

Estrogen receptor antagonist/ partial agonist. May be used in genome engineering (e.g. CreER/ CRISPR-Cas9). Citrate salt.

Selective D₁-D₂ heteromer antagonist

Potent and selective orexin OX₂ antagonist

AT₁ antagonist and PPARγ partial agonist

Adenosine receptor antagonist

Selective 5-HT_1A agonist. α₁-adrenoceptor antagonist

Potent 5-HT_1A receptor antagonist. D₄ receptor agonist.

Novel, selective mGlu₇ antagonist

Potent, selective, non-competitive mGlu₁ antagonist

Potent 5-HT₃ antagonist and 5-HT₄ agonist. Also selective IK1 channel agonist.