Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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Items 1-10 of 19

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  1. AK-7 (HB3747)

    Description:

    Brain-permeable SIRT2 (sirtuin 2) inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $494
    Qty:
  2. Pack:
    5mg
    Price:
    $499
    Qty:
    Pack:
    10mg
    Price:
    $743
    Qty:
  3. Pack:
    10mg
    Price:
    $152
    Qty:
    Pack:
    50mg
    Price:
    $579
    Qty:
  4. Description:

    Phytotoxin. Derivative of the HDAC inhibitor chlamydocin.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $272
    Qty:
  5. Pack:
    5mg
    Price:
    $1,056
    Qty:
  6. Description:

    Endogenous HDAC1, HDAC3 and HDAC4 inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $54
    Qty:
    Pack:
    100mg
    Price:
    $118
    Qty:
  7. Description:

    Endogenous HDAC1, HDAC3 and HDAC4 inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $48
    Qty:
    Pack:
    100mg
    Price:
    $109
    Qty:
  8. Pack:
    25mg
    Price:
    $580
    Qty:
  9. MS-275 (HB3983)

    Description:

    HDAC 1 inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $310
    Qty:
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