Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μg
    Price:
    $197
    Qty:
    Pack:
    100μg
    Price:
    $442
    Qty:
  2. Description:

    Antibody to NeuN - marker for mature neurones expressed in the nucleus. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μg
    Price:
    $144
    Qty:
    Pack:
    100μg
    Price:
    $320
    Qty:
  3. Description:

    Goat Anti-Chicken IgG H&L Horseradish peroxidase (HRP) secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Pack:
    1mL
    Price:
    $150
    Qty:
  4. Description:

    Goat Anti-Mouse IgG H&L AF488 secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Pack:
    500μg
    Price:
    $130
    Qty:
    Pack:
    1mg
    Price:
    $194
    Qty:
  5. Description:

    Goat Anti-Mouse IgG H&L (Biotin) preadsorbed secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Pack:
    500μg
    Price:
    $113
    Qty:
    Pack:
    1mg
    Price:
    $185
    Qty:
  6. Description:

    Goat Anti-Mouse IgG H&L Horseradish peroxidase (HRP) secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Pack:
    1mL
    Price:
    $177
    Qty:
  7. Description:

    Goat Anti-Mouse IgG H&L Janelia Fluor® 525 secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Pack:
    500μg
    Price:
    $143
    Qty:
    Pack:
    1mg
    Price:
    $238
    Qty:
  8. Description:

    Goat Anti-Mouse IgG H&L Janelia Fluor® 549 secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Pack:
    500μg
    Price:
    $143
    Qty:
    Pack:
    1mg
    Price:
    $238
    Qty:
  9. Description:

    Goat Anti-Mouse IgG H&L Janelia Fluor® 646 secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Pack:
    500μg
    Price:
    $139
    Qty:
    Pack:
    1mg
    Price:
    $231
    Qty:
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