Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 14

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  1. Pack:
    100mg
    Price:
    $318
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    Pack:
    500mg
    Price:
    $1,268
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  2. BINA (HB0133)

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    Description:

    Potent, selective mGlu2 positive allosteric modulator

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $140
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    Pack:
    10mg
    Price:
    $237
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    Pack:
    25mg
    Price:
    $439
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  3. Pack:
    10mg
    Price:
    $131
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    Pack:
    50mg
    Price:
    $519
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  4. CIQ (HB0197)

    1  Review
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    Description:

    GluN2C / GluN2D subunit selective NMDA receptor positive allosteric modulator

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $174
    Qty:
    Pack:
    50mg
    Price:
    $700
    Qty:
  5. Cyclothiazide (HB0221)

    2  Reviews
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    Description:

    AMPA receptor positive allosteric modulator. Inhibits AMPAR desensitization.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $66
    Qty:
    Pack:
    50mg
    Price:
    $272
    Qty:
  6. Pack:
    10mg
    Price:
    $108
    Qty:
    Pack:
    50mg
    Price:
    $439
    Qty:
  7. Pack:
    25mg
    Price:
    $417
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  8. Pack:
    50mg
    Price:
    $62
    Qty:
  9. UBP709 (HB9204)

    Description:

    NMDAR pan-PAM that potentiates all GluN2 subunits. Enhances LTD and decreases LTP. 

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $186
    Qty:
    Pack:
    50mg
    Price:
    $767
    Qty:
  10. Description:

    NMDAR PAM which potentiates GluN2A and GluN2B with minimal effects on 2C and 2D.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $182
    Qty:
    Pack:
    50mg
    Price:
    $690
    Qty:
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