Histone deacetylase (HDAC)
Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.
SB 269970 hydrochloride (HB1684)
Description:Potent, selective 5-HT7 receptor antagonist
Purity:>98%
SCH 23390 hydrochloride (HB1643)
Description:Potent, selective D1-like receptor antagonist
Purity:>98%
SKF 83566 hydrobromide (HB1863)
Description:Potent, selective D1-like receptor antagonist
Purity:>98%
Spiperone hydrochloride (HB1656)
Description:Selective D2-like receptor antagonist. 5-HT2A antagonist.
Purity:>98%
Spironolactone (HB2799)
Description:Mineralocorticoid and androgen receptor antagonist
Purity:>98%
SR 95531 hydrobromide (Gabazine) (HB0901)
Description:Selective, competitive GABAA receptor antagonist
Purity:>98%
(S)-(-)-Sulpiride (HB1836)
Description:Selective D2-like receptor antagonist. Active enantiomer.
Purity:>99%
(RS)-(±)-Sulpiride (HB1835)
Description:Standard D2-like dopamine receptor antagonist
Purity:>98%
Talampanel (HB0600)
Description:Selective, non-competitive AMPA / kainate receptor antagonist
Purity:>98%