Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligand

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $143
    Free trial
    Qty:
    Pack:
    50mg
    Price:
    $626
    Qty:
  2. Dexamethasone (HB2521)

    Description:

    Anti-inflammatory synthetic glucocorticoid. Induces hMSC differentiation. Apoptosis inducer.

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $68
    Qty:
    Pack:
    1g
    Price:
    $317
    Qty:
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    Description:

    Synthetic glucocorticoid with potent anti-inflammatory actions. Induces hMSC differentiation. Apoptosis inducer. Water soluble and suitable for cell culture. 

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $109
    Qty:
  4. Description:

    Water soluble Toll-like receptor 7 (TLR7) agonist. Stimulates cytokine production.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $29
    Qty:
    Pack:
    50mg
    Price:
    $52
    Qty:
    Pack:
    100mg
    Price:
    $77
    Qty:
    Pack:
    250mg
    Price:
    $147
    Qty:
  5. Description:

    Potent, selective µ-opioid receptor agonist

    Purity:

    >99%

    Pack:
    1g
    Price:
    $59
    Qty:
  6. Pam2CSK4 (HB3086)

    Description:

    TLR2/6 activator. Induces potent NF-κB activation and cytokine production.

    Pack:
    1mg
    Price:
    $159
    Qty:
  7. Pam3CSK4 (HB3428)

    Description:

    TLR1/TLR2 agonist and potent NF-κB activator. Induces cytokine production.

    Pack:
    1mg
    Price:
    $153
    Qty: