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Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Antibody Diluent (HB8223)

    Description:

    Diluent used to dilute primary antibodies or for storage

    Pack:
    125mL
    Price:
    $131
    Qty:
    Pack:
    250mL
    Price:
    $222
    Qty:
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  2. Biotinyl Tyramide (HB18327)

    Description:

    Biotin reagent used for signal enhancement in IHC, ISH,  and APEX proximity labelling

    Purity:

    >98%

    Biotinyl Tyramide
    Pack:
    25mg
    Price:
    $60
    Qty:
    Supporting Docs Add to Favorites

  3. Goat Anti-Chicken IgY H&L (HRP) ValidAbâ„¢ (HB9914)

    Description:

    Goat Anti-Chicken IgG H&L Horseradish peroxidase (HRP) secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Figure 3. HB9914 shows extremely high sensitivity producing bands down to a 1:2,000,000 dilution
    Pack:
    1mL
    Price:
    $150
    Qty:
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  4. Goat Anti-Mouse IgG H&L (Biotin) preadsorbed ValidAbTM (HB11345)

    Description:

    Goat Anti-Mouse IgG H&L (Biotin) preadsorbed secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Figure 1. Parvalbumin and Calretinin expressing interneurons in the rat hippocampus.
    Pack:
    500μg
    Price:
    $113
    Qty:
    Pack:
    1mg
    Price:
    $185
    Qty:
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  5. Goat Anti-Mouse IgG H&L (HRP) preadsorbed ValidAbâ„¢ (HB8356)

    Description:

    Goat Anti-Mouse IgG H&L Horseradish peroxidase (HRP) secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Figure 3. HB8356 shows extremely high sensitivity producing bands down to a 1:2,000,000 dilution.
    Pack:
    1mL
    Price:
    $177
    Qty:
    Supporting Docs Add to Favorites

  6. Goat Anti-Rabbit IgG H&L (Biotin) preadsorbed ValidAbTM (HB11036)

    Description:

    Goat Anti-Rabbit IgG H&L (Biotin) preadrorbed secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Figure 1. Calretinin positive interneurons and astrocytes in the rat hippocampus.
    Pack:
    500μg
    Price:
    $113
    Qty:
    Pack:
    1mg
    Price:
    $171
    Qty:
    Supporting Docs Add to Favorites

  7. Goat Anti-Rabbit IgG H&L (HRP) preadsorbed ValidAbâ„¢ (HB9524)

    Description:

    Goat Anti-Rabbit IgG H&L Horseradish peroxidase (HRP) secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Goat
    Clonality: Polyclonal
    Figure 3. HB9524 shows extremely high sensitivity producing bands down to a 1:2,000,000 dilution.
    Pack:
    1mL
    Price:
    $177
    Qty:
    Supporting Docs Add to Favorites

  8. Streptavidin AF488 (HB13531)

    Description:

    AF488 conjugated streptavidin for detection and signal amplification of biotin coupled proteins and antibodies.

    Figure 1. Parvalbumin and Calretinin expressing interneurons in the rat hippocampus.
    Pack:
    1mg
    Price:
    $155
    Qty:
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  9. Streptavidin Janelia Fluor® 525 (HB15382)

    Description:

    Janelia Fluor® 525 conjugated streptavidin for detection and signal amplification of biotin coupled proteins and antibodies.

    Figure 1. Parvalbumin and Calretinin expressing interneurons in the rat hippocampus.
    Pack:
    1mg
    Price:
    $155
    Qty:
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  10. Streptavidin Janelia Fluor® 549 (HB18064)

    Description:

    Janelia Fluor® 549 conjugated streptavidin for detection and signal amplification of biotin coupled proteins and antibodies.

    Figure 1: Parvalbumin positive interneuron cells in the rat hippocampus.
    Pack:
    1mg
    Price:
    $155
    Qty:
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Category
Biological action
  1. Buffer
Applications
  1. Antineoplastic Agent
  2. Cell Culture
  3. ELISA
  4. FACS and flow cytometry
  5. fluorescence imaging
  6. ICC
  7. IF
  8. IHC
  9. IHC-P
  10. live cell imaging
  11. Plant Culture
  12. Selection Agent
  13. WB
  14. IHC(IF)
  15. Histoblot
  16. SDS-PAGE
Host
  1. Goat
Clonality
  1. Polyclonal
Conjugate
  1. Horseradish peroxidase (HRP)
  2. Biotin
Target
  1. Mouse IgG H&L
  2. Rabbit IgG H&L
  3. Histone H3
  4. Chicken IgY H&L
  5. Biotin