Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Actinomycin D (HB1477)

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    Description:

    RNA polymerase inhibitor. Apoptosis inducer.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $129
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    Pack:
    5mg
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    Pack:
    100mg
    Price:
    $925
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    Pack:
    25mg
    Price:
    $243
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  2. Pack:
    5g
    Price:
    $49
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    Pack:
    25g
    Price:
    $166
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  3. Description:

    Identifies early apoptotic, necrotic and viable cells

    Pack:
    100 tests
    Price:
    $563
    Qty:
  4. Cycloheximide (HB2904)

    Description:

    Eukaryotic protein synthesis inhibitor. Apoptosis inducer.

    Purity:

    >95%

    Pack:
    1g
    Price:
    $54
    Qty:
  5. Pack:
    100 tests
    Price:
    $132
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    Pack:
    300 tests
    Price:
    $264
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  6. Pack:
    250mg
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    Pack:
    1g
    Price:
    $89
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  7. Pack:
    50mg
    Price:
    $40
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    Pack:
    250mg
    Price:
    $149
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    Pack:
    1g
    Price:
    $240
    Qty:
  8. Pack:
    1g
    Price:
    $36
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    Pack:
    5g
    Price:
    $55
    Qty:
  9. Mitomycin C (HB4458)

    Description:

    Antibiotic. DNA synthesis inhibitor.

    Purity:

    >97%

    Pack:
    5mg
    Price:
    $77
    Qty:
    Pack:
    25mg
    Price:
    $299
    Qty:
  10. Description:

    Protein synthesis inhibitor. Cell culture selection antibiotic.

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $49
    Qty: