Target

TRPV1 channel antagonist

ACE and LTA₄ hydrolase inhibitor

Competitive, selective group 1 mGlu antagonist

NO scavenger

K_2P2.1 (TREK-1) modulator. Used with ML336 as part of the CATKLAMP chemogenetic strategy. Selectively and irreversibly activates TREK-1^CG* but not wild-type K_2P2.1 (TREK-1)

Selective mGlu₅ positive allosteric modulator

β-lactam antibiotic. Increases EAAT2 activity.

Anti-oxidant, anti-inflammatory compound with many actions. Topoisomerase II inhibitor.

Potent and specific PKC inhibitor

Potassium channel blocker. Component in cesium gluconate-based internal solutions used for patch clamp electrophysiology.