JAK/STAT
JAK/STAT signaling plays a critical role in the immune response. It is plays a major role in transferring signals from cell-membrane receptors to the nuclear. The JAK/STAT signaling pathway is essential for a wide range of cytokines and growth factors which lead to critical immunological cellular events.
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LUF7487 (HB9585)
Description:Novel, covalent Affinity-Based Probe (AfBP). Clickable antagonist for the A2AR.
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Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.
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LY-367385 hydrochloride (HB5153)
Description:Potent, highly selective mGlu1a antagonist. Water soluble.
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