Cytoskeleton and Extracellular Matrix
The cytoskeleton acts as a cellular scafforld within a cell and plays an important role in many processes such as cell motility and cell division. Many cytoskeletal proteins interact with proteins of the extracellular matrix (ECM). The ECM is a network of extracellular molecules which provide structural and biochemical support to surrounding. The ECM is vital to cellular processes including proliferation, adhesion, migration, polarity, differentiation, and apoptosis.
Researchers can save up to 50% on Cytoskeleton and Extracellular Matrix products from Hello Bio - they are up to half the price of other suppliers.
View products: Actin | Matrix Metalloproteases (MMP) | PI3K/Akt/mTOR | Microtubule | ROCK (Rho-kinase)
SB 202190 (HB1301)
Description:Potent ATP competitive p38 MAPK inhibitor. 3D growth matrix component, promotes long-term organoid growth and can be used in production of gastric organoids. Promotes stability of human pluripotent stem cells.
Purity:>99%
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SB 203580 (HB1302)
Description:Potent, selective p38 MAPK inhibitor. Stimulates neural stem cell proliferation.
Purity:>98%
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SB 216763 (HB1272)
Description:Potent, selective cell permeable GSK-3 inhibitor. Maintains mESCs and promotes retinal stem cells proliferation.
Purity:>98%
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SB 431542 (HB3555)
Description:Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.
Purity:>98%
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Sodium butyrate (HB1399)
Description:HDAC inhibitor. Directs mESC differentiation into hepatocytes.
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SP600125 (HB2234)
Description:Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.
Purity:>98%
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