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Reported to be a potent, selective Ca_v2.3 (R-type) channel blocker

Potent, selective ASIC1a blocker

Potassium channel blocker. Component in cesium gluconate-based internal solutions used for patch clamp electrophysiology.

CNS stimulant

Na⁺ channel blocker / glutamate inhibitor. TREK-1 K2P channel activator. Water soluble.

Potent, selective K_Ca1.1 channel activator

Potent competitive NMDA antagonist

GluN2C/D selective, non-competitive NMDA receptor antagonist

L-type calcium channel blocker

Potent, selective, competitive P2X receptor antagonist