Transporters
Transporters are integral transmembrane proteins involved in the movement of ions, small molecules, peptides, lipids or macromolecules, such as another protein, across a biological membrane. The energy required for active transport processes is obtained by hyrdolyzing ATP or by utilising ion gradients. The three major classes of ATP-driven transporters are: P-type ATPases (eg. Ca2+-ATPases and Na+,K+-ATPases); F-type or V-type ATPases and ATP-binding cassette transporters. The solute carrier family of transporters include the biogenic amine transporters (NET, DAT and SERT) the Na+/H+ exchanger, glutamate transporters (EAAT) and GABA transporters (GAT). Researchers can save up to 50% on transporter blockers and inhibitors from Hello Bio – they are up to half the price of other suppliers and have been reviewed and cited by researchers worldwide.
View transporter products: Cannabinoid | Dopamine | GABA | Glutamate | Glycine | Monoamine | Multidrug Transporter | Na+ / Ca2+ exchangers | Na+ / H+ exchangers | Norepinephrine | Serotonin (5-HT)
GBR 12909 dihydrochloride (HB1812)
Description:Potent, competitive dopamine uptake inhibitor
Purity:>98%
KB-R7943 mesylate (HB1133)
Description:Selective, reverse mode Na+ / Ca2+ exchange inhibitor
Purity:>99%
Milnacipran hydrochloride (HB1759)
Description:5-HT and norepinephrine re-uptake inhibitor (SNRI)
Purity:>99%
N-Arachidonylglycine (NAGly) (HB0439)
Description:Endogenous GLYT2 inhibitor / Cav3.1 / 3.2 / 3.3 current inhibitor
Paroxetine hydrochloride (HB0478)
Description:Potent, selective serotonin reuptake inhibitor. Selective GRK2 inhibitor.
Purity:>99%
Sertraline hydrochloride (HB1717)
Description:Potent, selective 5-HT re-uptake inhibitor (SSRI)
Purity:>98%
SKF 89976A hydrochloride (HB0976)
Description:Potent, selective, competitive GAT-1 GABA uptake inhibitor
Purity:>99%
Tetrabenazine (HB1711)
Description:Potent inhibitor of vesicular monoamine transport; depletes 5-HT stores
Purity:>98%