Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
CGP 54626 hydrochloride (HB0959)
Description:Potent, selective GABAB receptor antagonist
Purity:>98%
CGP 55845 hydrochloride (HB0960)
Description:Potent, selective GABAB receptor antagonist
Purity:>98%
CNQX disodium salt (HB0205)
Description:Potent, competitive AMPA / kainate receptor antagonist. Disodium salt.
Purity:>98%
GYKI 52466 hydrochloride (HB0311)
Description:Selective, non-competitive AMPA receptor antagonist
Purity:>98%