DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 261-270 of 320

Set Descending Direction
  1. Spadin (HB5438)

    Description:

    Potent TREK-1/ K2P2.1 channel blocker. Shows fast-acting antidepressant effects.

    Pack:
    1mg
    Price:
    $127
    Qty:
  2. Pack:
    10mg
    Price:
    $246
    Qty:
    Pack:
    50mg
    Price:
    $968
    Qty:
  3. Stattic (HB1437)

    Description:

    Selective STAT3 inhibitor

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $63
    Qty:
    Pack:
    25mg
    Price:
    $254
    Qty:
  4. Stauprimide (HB3011)

    Description:

    NME2 nuclear translocation inhibitor. Primes ESCs for differentiation.

    Purity:

    >98%

    Pack:
    100μg
    Price:
    $188
    Qty:
  5. Pack:
    1mg
    Price:
    $408
    Qty:
  6. Pack:
    10mg
    Price:
    $235
    Qty:
    Pack:
    50mg
    Price:
    $887
    Qty:
  7. SU 5402 (HB3133)

    Description:

    Potent FGFR and VEGFR inhibitor. Attenuates integrin β4-induced neural stem cell differentiation.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $138
    Qty:
  8. TAK 715 (HB0599)

    Description:

    Potent, p-38 MAP kinase inhibitor. Wnt/β-catenin signaling inhibitor.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $209
    Qty:
    Pack:
    50mg
    Price:
    $825
    Qty:
  9. TAT-GluR6-9c (HB9357)

    Description:

    GluK6-PSD-95 interaction inhibitor

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $200
    Qty:
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