Ionotropic glutamate receptors
Ionotropic glutamate receptors (NMDA, AMPA and Kainate receptors) are cation-selective tetramers formed by multimeric assemblies of subunits. AMPA receptors comprise of homomers or heteromers of GluA1, GluA2, GluA3 and GluA4 subunits. NMDA receptors are heteromic assemblies of GluN1, GluN2A, GluN2B, GluN2C, GluN2D, GluN3A and GluN3B. Kainate receptors can be expressed as homomers of GluK1, GluK2 or GluK3. Researchers can save up to 50% on potent & selective NMDA, AMPA and Kainate receptor antagonists, agonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
View resources: Ionotropic Receptor Nomenclature Guide | NMDA Receptor Mini-Review | NMDAR Associated Proteins
View products:Â AMPA | Kainate | NMDA
A83-01 (HB3218)
Description:Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Purity:>98%
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Aphidicolin (HB3690)
Description:DNA replication inhibitor. Useful for cell synchronization
Purity:>98%
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5-aza-2'-deoxycytidine (Decitabine) (HB1356)
Description:DNA methyltransferase inhibitor
Purity:>99%
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5-Azacytidine (HB1374)
Description:DNA methyltransferase inhibitor. Improves stem cell reprogramming efficiency and induces differentiation of MSCs into cardiomyocytes.
Purity:>98%
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BIO (HB1259)
Description:Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.
Purity:>98%
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BIX 01294 (HB1413)
Description:Potent, selective GLP / G9a HMTase inhibitor. Potentiates iPSC induction.
Purity:>98%
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Brefeldin A (BFA) (HB2949)
Description:Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.
Purity:>98%
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Calyculin A (HB0161)
Description:Potent, selective protein phosphatase 1 / 2A inhibitor
Purity:>98%
