Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Potent, highly selective iNOS inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $192
    Qty:
  2. A83-01 (HB3218)

    2  Reviews
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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $92
    Qty:
    Pack:
    25mg
    Price:
    $310
    Qty:
  3. Pack:
    5mg
    Price:
    $85
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    Pack:
    10mg
    Price:
    $122
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    Pack:
    25mg
    Price:
    $287
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    Pack:
    50mg
    Price:
    $485
    Qty:
  4. Pack:
    10mg
    Price:
    $358
    Qty:
  5. Actinomycin D (HB1477)

    9  Reviews
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    Description:

    RNA polymerase inhibitor. Apoptosis inducer.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $129
    Qty:
    Pack:
    5mg
    Price:
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    Pack:
    100mg
    Price:
    $925
    Qty:
    Pack:
    25mg
    Price:
    $243
    Qty:
  6. AM 404 (HB1174)

    Description:

    Selective, competitive carrier-mediated anandamide transport inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $66
    Qty:
    Pack:
    50mg
    Price:
    $263
    Qty:
  7. Pack:
    10mg
    Price:
    $165
    Qty:
    Pack:
    50mg
    Price:
    $656
    Qty:
  8. 2  Reviews
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    Description:

    Non-selective voltage gated K+ channel blocker

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $69
    Qty:
  9. Description:

    Serotonin/norepinephrine reuptake inhibitor (SNRI)

    Purity:

    >98%

    Pack:
    1g
    Price:
    $131
    Qty:
  10. Pack:
    100mg
    Price:
    $58
    Qty:
    Pack:
    1g
    Price:
    $449
    Qty:
    Pack:
    100mM (add 1ml water)
    Price:
    $42
    Qty:
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