Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  5. Description:

    Blue fluorescent DNA stain. Nuclear stain. 10mg/ml staining solution in water. Solid also available in 50mg and 100mg.

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    5ml (1mg/mL)
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    $124
    Free trial
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    10mL (10mg/mL)
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  6. JC-1 (HB0791)

    Description:

    Mitochondrial membrane potential indicator/dye. Widely used in apoptosis studies.

    Purity:

    >95%

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    5mg
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    $460
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  7. MTT (HB5283)

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    Description:

    Dye commonly used for cell proliferation measurement

    Pack:
    500mg
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    $44
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    1g
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    $65
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  8. Description:

    Oxazole Yellow iodide is also known as Yo-Pro-1. It is a commonly used apoptosis marker.

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    1mg
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    $208
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  9. Description:

    Oxazole Yellow iodide is also known as Yo-Pro-1. It is a commonly used apoptosis marker. 1mM solution (in 1mL DMSO)

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    1mL
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    $274
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