Target

Potent, selective, use-dependent Na⁺ channel blocker. Citrate free.

Potent, selective, use-dependent Na⁺ channel blocker. Citrate Salt.

Potent, non-competitive SERCA inhibitor

Selective GAT-1 GABA uptake inhibitor

Selective 5-HT uptake enhancer

Potent, selective mTOR inhibitor

TRPV2 channel inhibitor. Potent mast cell stabilizer.

Potent 5-HT₃ receptor antagonist. Also α7 nAChR partial agonist. Activates α7Q79G-GlyR chimeric ion channels.

Novel, potent, subtype-selective TRPV3 inhibitor

ER Stress inducer which induces cell death