Proliferation, self-renewal, maintenance
Stem cells have the ability to replicate continually. Proliferation is when a cell multiplies but does not change its cell type. Self renewal is the process of a stem cell dividing to produce at least one copy of itself. Small molecules such as SB 203580 and PGE2 stimulate proliferation. Researchers can save up to 50% on small molecules which modulate stem cell proliferation, self-renewal and maintenance from Hello Bio - they are up to half the price of other suppliers.Â
A83-01 (HB3218)
Description:Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Purity:>98%
SB 431542 (HB3555)
Description:Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.
Purity:>98%
ROCK inhibitor Y-27632 (HB2297)
Description:Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.
Purity:>99%