Organoids

Organoids are 3D tissue/organ models made up of pluripotent stem cells and other supporting co-cultured cells eg. epithelial cells. Many types of organoids have been developed to date, including brain, pancreas, heart, lung, intestine, liver, optic cup and cancer organoids. They make stable model systems and can be derived from human stem cells or from patient derived iPSCs. Small molecules are increasingly being used to grow and maintain organoids because of their ease of use and controllable quality, enabling consistent, repeatable results. Researchers can save up to 50% on high purity small molecules used to generate organoids – the range from Hello Bio is around half the price of other suppliers.

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  1. A83-01 (HB3218)

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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $92
    Qty:
    Pack:
    25mg
    Price:
    $310
    Qty:
  2. AG 490 (HB1424)

    Description:

    Selective EGF receptor tyrosine kinase inhibitor

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $478
    Qty:
  3. AM 404 (HB1174)

    Description:

    Selective, competitive carrier-mediated anandamide transport inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $66
    Qty:
    Pack:
    50mg
    Price:
    $263
    Qty:
  4. Description:

    Serotonin/norepinephrine reuptake inhibitor (SNRI)

    Purity:

    >98%

    Pack:
    1g
    Price:
    $131
    Qty:
  5. Pack:
    10mg
    Price:
    $164
    Qty:
    Pack:
    50mg
    Price:
    $592
    Qty:
  6. Description:

    Irreversible tryptophan hydroxylase inhibitor. Depletes 5-HT.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $59
    Qty:
  7. Pack:
    10mg
    Price:
    $68
    Qty:
    Pack:
    50mg
    Price:
    $205
    Qty:
  8. Cyclopamine (HB2965)

    Description:

    Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $205
    Qty:
    Pack:
    5mg
    Price:
    $779
    Qty:
  9. Pack:
    10mg
    Price:
    $215
    Qty:
    Pack:
    50mg
    Price:
    $836
    Qty:
  10. Pack:
    5mg
    Price:
    $80
    Qty:
    Pack:
    25mg
    Price:
    $320
    Qty:
    Pack:
    10mg
    Price:
    $76
    Qty:
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