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JAK/STAT
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JAK/STAT signaling plays a critical role in the immune response. It is plays a major role in transferring signals from cell-membrane receptors to the nuclear. The JAK/STAT signaling pathway is essential for a wide range of cytokines and growth factors which lead to critical immunological cellular events.
Pluripotin (HB2223)
Description:Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal.
Purity:>98%
SB 202190 (HB1301)
Description:Potent ATP competitive p38 MAPK inhibitor. 3D growth matrix component, promotes long-term organoid growth and can be used in production of gastric organoids. Promotes stability of human pluripotent stem cells.
Purity:>99%
SB 203580 (HB1302)
Description:Potent, selective p38 MAPK inhibitor. Stimulates neural stem cell proliferation.
Purity:>98%
SP600125 (HB2234)
Description:Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.
Purity:>98%