Inflammasome

Inflammasomes are an important part of the innate immune system which are activated upon cellular infection or stress to trigger maturation of proinflammatory cytokines. They regulate the activation of caspase-1 and induce an inflammatory response.
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  1. A83-01 (HB3218)

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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $92
    Qty:
    Pack:
    25mg
    Price:
    $310
    Qty:
  2. AM 404 (HB1174)

    Description:

    Selective, competitive carrier-mediated anandamide transport inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $66
    Qty:
    Pack:
    50mg
    Price:
    $263
    Qty:
  3. Description:

    Serotonin/norepinephrine reuptake inhibitor (SNRI)

    Purity:

    >98%

    Pack:
    1g
    Price:
    $131
    Qty:
  4. Description:

    Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $110
    Qty:
    Pack:
    25mg
    Price:
    $481
    Qty:
  5. Calphostin C (HB0160)

    Description:

    Potent, selective PKC inhibitor. Also antagonizes the Tcf/β-catenin complex

    Purity:

    >95%

    Pack:
    100μg
    Price:
    $239
    Qty:
    Pack:
    1mg
    Price:
    $1,215
    Qty:
  6. Pack:
    10μg
    Price:
    $182
    Qty:
  7. CHIR 99021 (HB1261)

    Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $50
    Qty:
    Pack:
    2mg
    Price:
    Qty:
    Pack:
    5×2mg
    Price:
    $188
    Qty:
    Pack:
    10mg
    Price:
    $182
    Qty:
    Pack:
    5mg
    Price:
    $117
    Qty:
    Pack:
    25mg
    Price:
    $445
    Qty:
    Pack:
    50mg
    Price:
    $758
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $126
    Qty:
  8. Pack:
    10mg
    Price:
    $133
    Qty:
    Pack:
    50mg
    Price:
    $597
    Qty:
  9. Pack:
    5mg
    Price:
    $80
    Qty:
    Pack:
    25mg
    Price:
    $320
    Qty:
    Pack:
    10mg
    Price:
    $76
    Qty:
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