Microtubule

Potent, reversible AMPK activator. Inhibits MSC proliferation.

AMPK activator. Promotes osteogenic differentiation of bone marrow-derived MSCs.

Caspase activator. Apoptosis inducer.

Member of the neurotrophin growth factor family. Plays an important role in synaptic plasticity and neurogenesis.

Potent K_Ca1.1 channel activator

Cell permeable PKA activator

Ceramide-activated protein phosphatase (CAPP) activator

K_2P2.1 (TREK-1) modulator. Used with ML336 as part of the CATKLAMP chemogenetic strategy. Selectively and irreversibly activates TREK-1^CG* but not wild-type K_2P2.1 (TREK-1)

Antimalarial. Apoptosis and autophagy inhibitor.

Prototypical DREADD activator. Clozapine metabolite.