Cytokine Storm / Immune response signaling
Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.
View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling
- Description:
Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.
LY 294002 hydrochloride (HB2266)
Description:PI3-K inhibitor. Suppresses mESC proliferation.
Purity:>99%
MCC950 sodium salt (HB4636)
Description:Potent, selective NLRP3 inflammasome inhibitor
Purity:>98%
Monensin sodium salt (HB4882)
Description:Protein transport inhibitor. Commonly used in cytokine staining.
Purity:>98%
Niclosamide (HB1435)
Description:STAT3 signaling pathway inhibitor. Antineoplastic against AML stem cells.
Purity:>98%