DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
Recombinant human GDNF protein (HB5735)
Description:Neurotrophin which enhances differentiation and survival of dopaminergic neurons
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Growth factor implicated in various nervous system functions.
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Growth factor implicated in various nervous system functions.
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Tissue globin widely expressed in neurons CNS and PNS
Recombinant human NT-3 protein (HB8373)
Description:Neurotrophin involved in neuron development, survival and differentiation
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Multifunctional protein with neurotrophic, anti-angiogenic and anti-tumorigenic properties
Recombinant mouse beta-NGF protein (HB9755)
Description:Recombinant mouse neurotrophic factor related to BDNF, NT-3 and NT-4
Recombinant mouse MANF protein (HB6565)
Description:Neurotrophic factor with neuroprotective effects